MOTS-C

Peptide Product Fields

Peptide Purity

99.762%

Peptide Average Mass

11.81 mg

Peptide Summary

MOTS-c: It tricks your body into thinking it's working out. It tells your cells to stop storing fat and start burning it for energy instead. It's great for improving your metabolism, giving you more energy, and helping with weight management.

Peptide Mechanism

MOTS-c: MOTS-c is a peptide derived from mitochondria that regulates energy metabolism by enhancing insulin sensitivity, promoting fat oxidation, and influencing the AMPK pathway, which helps cells utilize glucose more effectively.

Peptide Recommendations

MOTS-c: All doses are subcutaneous injection. Administer 30-45 minutes before a meal or fasted in the morning. Goal | Dose | Frequency Standard | 5 mg | 2-3 times per week More aggressive | 10 mg | 2-3 times per week

Peptide Timing

MOTS-c: Administer 30-45 minutes before the largest meal of the day, or in the morning fasted for best metabolic effect.

Peptide Cycling Protocol

MOTS-c: 4-8 weeks on, 2-4 weeks off. Cycling is recommended to prevent metabolic adaptation.

Peptide Side Effect Notes

MOTS-c: Potential side effects include fatigue or temporary energy fluctuations, nausea, headaches, and increased heart rate. Start at the lower end of the dose range to assess tolerance.

Peptide Quick Dose

Peptide: MOTS-c; Dose Range: 5-10 mg; Frequency: 2-3x per week; Timing / Notes: Morning or pre-workout. 4-8 weeks on.

Peptide Stack Protocols

1. The Retatrutide Energy & Mitochondrial Stack Retatrutide + NAD+ + SS-31 (+ optional MOTS-c) The Goal: Combat the fatigue and energy drain that often comes with the calorie deficit caused by Retatrutide, while maximizing fat burning at the cellular level. How it works: Retatrutide handles the appetite suppression and metabolic baseline. However, eating significantly less can leave you feeling drained. NAD+ provides the raw cellular fuel to keep your energy up, while SS-31 repairs the mitochondria so they can actually use that fuel efficiently. MOTS-c can be added to further enhance insulin sensitivity and push the muscles to burn fat for energy. Peptide | Dose | Frequency | Time of Day Retatrutide | 0.5-2 mg (start low) | Once weekly | Any consistent day NAD+ | 25-50 mg SubQ | 3x per week (Mon/Wed/Fri) | Morning SS-31 | 10 mg | Daily or 5x per week | Morning MOTS-c (optional) | 5-10 mg | 2-3x per week | Morning, fasted Day | What to Take Monday | Retatrutide + NAD+ + SS-31 + MOTS-c (if using) Tuesday | SS-31 Wednesday | NAD+ + SS-31 Thursday | SS-31 Friday | NAD+ + SS-31 + MOTS-c (if using) Saturday | SS-31 Sunday | Rest Cycle: Run continuously alongside Retatrutide. NAD+ and SS-31 do not require a break. MOTS-c: 4-8 weeks on, 2-4 weeks off.

Peptide Comparison Notes

2. Weight Loss & Metabolism: Retatrutide vs. 5-Amino-1MQ vs. MOTS-c vs. SLU-PP-332 Retatrutide is the heavy hitter. It works on the brain and gut to drastically reduce appetite and slow digestion. It is the most powerful tool for significant weight loss. 5-Amino-1MQ works at the cellular level. It doesn't stop you from eating; instead, it blocks the enzyme that tells your body to store fat, forcing your body to burn it instead. MOTS-c improves insulin sensitivity and tells your cells to use energy more efficiently, mimicking the metabolic effects of exercise. SLU-PP-332 is an exercise mimetic that specifically increases endurance and fat oxidation in muscle tissue.